Submitted by Anonymous (not verified) on Mon, 30/03/2020
Written by Jennifer Mercer, supported by Janet Baker
Physical activity (PA) is defined as any skeletal muscle movement that requires energy (World Health Organisation, 2019). Whilst patients are undergoing treatment for haematological malignancies (HM), PA may reduce dramatically. Due to treatment side effects such as nausea/vomiting, cancer-related fatigue (CRF) and mucositis, a majority of patients will spend a large percentage of their day in an inactive state. In addition, due to neutropenia/risk of infection, patients may be in protective isolation, further restricting PA (Annibali et al., 2017).
Alibhai, S.M.H., Breunis, H., Matelski, J., Timilshina, N., Kundra, A., Lee, C.H., and Li, M. (2019) ‘Age-Related Cytokine Effects on Cancer-Related Fatigue and Quality of Life in Acute Myeloid Leukaemia’, Journal of Geriatric Oncology, 18, pp.1-8.
Annibali, O., Pensieri, C., Tomarchio, V., Biagioli, V., Pennacchini, M., Tendas, A., Tambone, V., and Tirindelli, M.C. (2017) ‘Protective Isolation for Patients with Haematological Malignancies: A Pilot Study Investigating Patients’ Distress and Use of Time’, International Journal of Hematology-Oncology and Stem Cell Research, 11(4), pp.313-318.
Argent, R., Daly, A., and Caulfield, B. (2018) ‘Patient Involvement with Home-Based Exercise Programs: Can Connected Health Interventions Influence Adherence?’, JMIR mHealth uHealth, 6(3), pp.1-23.
Arora, A. (2017) Time to Move: Get Up, Get Dressed, Get Moving. Available at: https://www.england.nhs.uk/blog/amit-arora/. Accessed 20/12/2019.
Bellettiere, J. Nguyen, B., Liles, S., Berardi, V., Adams, M.A., Dempsey, P., Benporat, Y., Kerr, J., LaCroix, A.Z., and Hovell, M. (2018) ‘Prompts to Increase Physical Activity at Points-of-Choice between Stairs and Escalators: What about Escalator Climbers?’, Translational Behavioural Medicine, 9, pp.656-662.
Bewarder, M., Klostermann, A., Ahlgrimm, M., Bittenbring, J.T., Pfreundschuh, M. Wagenpfeil, S., and Kaddu-Mulindwa, D. (2019) ‘Safety and Feasibility of Electrical Muscle Stimulation in Patients Undergoing’, Supportive Care in Cancer, 27(3), pp.1013-1020.
Blackburn, R., Presson, K., Laufman, R., Tomczak, N., and Brassil, K.J. (2016) ‘Establishing an Inpatient Gym for Recipients of Stem Cell Transplantation: A Multidisciplinary Collaborative’, Clinical Journal of Oncology Nursing, 20(1), pp.66-71.
Burger, R. (2013) ‘Impact of Interleukin-6 in Haematological Malignancies, Transfusion Medicine and Hemotherapy’, Transfusion Medicine and Hemotherapy, 40(5), pp.336-343.
Campbell, K.L., Winters-Stone, K.M., Wiskemann, J., May, A.M., Schwartz, A.L., Courneya, K.S., Zucker, D.S., Matthews, C.E., Ligibel, J.L., Gerber, L.H., Morris, G.S., Patel, A.V., Hue, T.F., Perna, F.M., and Schmitz, K.H. (2019) ‘Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary’, Medicine and Science in Sports and Exercise, 51(11), pp.2375-2390.
Cancer Research UK (2017) Fatigue and Cancer Drugs. Available at: https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatmen.... Accessed 06/12/2019.
Cha, S., Kim, I., Lee, S., and Seo, K.S. (2018) ‘Effect of an Inpatient Rehabilitation Program for Recovery of Deconditioning in Hematologic Cancer Patients After Chemotherapy’, Annals of Rehabilitation Medicine, 42(6), pp.838-845.
Chan, R.J., and Chan, A. (2015) ‘Survivorship Care Provision for Patients with Hematologic Malignancies' the Quest for Quality Evidence’, Cancer Nursing, 38(5), pp.414-415.
Clarke, C., Stack, C., and Martin, M. (2017) ‘Lack of meaningful activity on acute physical hospital wards: Older people’s experiences’, British Journal of Occupational Therapy, 81(1), pp.15-23.
Department of Health and Social Care (2019) UK Chief Medical Officers’ Physical Activity Guidelines. Available at: https://assets.publishing.service.gov.uk/government/uploads /system/uploads/attachment_data/file/832868/uk-chief-medical-officers-physical-activity-guidelines.pdf. Accessed 20/11/2019.
Duregon, F., Gobbo, S., Bullo, V., Roma, E., Vendramin, B., Bergamo, M., Bocalini, D.S. Di Blasio, A., Cugusi, L., Neunhaeuserer, D., Bergamin, M., and Ermolao, A. (2019) ‘Exercise Prescription and Tailored Physical Activity Intervention in Onco‐Hematology Inpatients, a Personalized Bedside Approach to Improve Clinical Best Practice’, Hematological Oncology, 37(3), pp.277-284.
Hacker, E.D., Collins, E., Park, C., Peters, T., Patel, P., and Rondelli, D. (2017) ‘Strength Training to Enhance Early Recovery after Hematopoietic Stem Cell Transplantation’, Biology of Blood and Bone Marrow Transplant, 23(4), pp.659-669.
Haematological Malignancy Research Network (2014) Patient’s age and treatment for haematological malignancy: a report from the Haematological Malignancy Research Network (HMRN). Available at: https://www.hmrn.org/Download.aspx? target=document&id=41. Accessed 02/01/2020.
Hari, P., Romanus, D., Luptakova, K., Blazer, M., Yong, C., Raju, A., Farrelly, E., Labotka, R., and Morrison, V.A. (2017) ‘The Impact of Age and Comorbidities on Practice Patterns and Outcomes in Patients with Relapsed/Refractory Multiple Myeloma in the Era of Novel Therapies’, Journal of Geriatric Oncology, 9(2), pp.138-144.
Hill, K.D., Hunter, S.W., Batchelor, F.A., Cavalheri, V., and Burton, E. (2015) ‘Individualized home-based exercise programs for older people to reduce falls and improve physical performance: A systematic review and meta-analysis’, Maturitas, 82(1), pp.72-84.
Khosravi, M., Masoumi, H.T., Gholami, K., Vaezi, M., Hadjibabaei, M., and Ghavamzadeh, A. (2018) ‘The Relationship between Fatigue and Cytokine Levels in Patients with Acute Myeloid Leukaemia’, International Journal of Haematologic Oncology Stem Cell Research, 12(4), pp.318-321.
Klepin, H.D., Tooze, J.A., Pardee, T.S., Ellis, L.R., Berenzon, D., Mihalko, S.L., Danhauer, S.C., Rao, A.R., Wildes, T.M., Williamson, J.D., Powell, B.L., and Kritchevsky, S.B. (2016) ‘Effect of Intensive Chemotherapy on Physical, Cognitive, and Emotional Health of Older Adults with Acute Myeloid Leukemia’, Journal of the American Geriatric Society, 64(10), pp.1988–1995.
Knips, L., Bergenthal, N., Streckmann, F., Monsef, I., Elter, T., and Skoetz, N. (2019) Aerobic physical exercise for adult patients with haematological malignancies. Available at: https://www.ncbi.nlm.nih.gov/pubmed/30702150. Accessed 22/11/2019.
Koll, T., and Rosko, A.E. (2018) ‘Frailty in Haematologic Malignancy’, Current Haematologic Malignancy Reports, 13(3), pp.143-154.
LaVoy, E.C.P., Fagundes, C.P., and Dantzer, R. (2016) ‘Exercise, Inflammation and Fatigue in Cancer Survivors’, Exercise Immunology Review, 22, pp.82-93.
Li, J., Smith, A., Crouch, S., Oliver, S., and Roman, E. (2016) ‘Estimating the prevalence of Haematological Malignancies and Precursor Conditions Using Data from Haematological Malignancy Research Network (HMRN)’, Cancer Causes Control, 27(8), pp.1019-1026.
Liang, Y., Zhou, M., Wang, F., and Wu, Z. (2018) ‘Exercise for physical fitness, fatigue and quality of life of patients undergoing hematopoietic stem cell transplantation: a meta-analysis of randomized controlled trials’, Japanese Journal of Clinical Oncology, 48(12), pp.1046–1057.
Macmillan Cancer Support (2018) Possible Side Effects of Chemotherapy. Available at: https://www.macmillan.org.uk/information-and-support/treating/chemothera.... Accessed 06/12/2019.
Meneses-Echavez, J.F., Correa-Bautista, J.E., Gonzalez-Jimenez, E., Schmidt Rio-Valle, J., Elkins, M.R., Lobelo, F., and Ramirez-Velez, R. (2016) ‘The Effect of Exercise Training on Mediators of Inflammation in Breast Cancer Survivors: A Systematic Review with Meta-Analysis’, Cancer Epidemiology, Biomarkers and Prevention, 25(7), pp.1009-1017.
Minton, O., Foster, J., and Maher, J. (2015) ‘The Roles of Behavioural Modification and Exercise in the Management of Cancer-Related Fatigue to Reduce its Impact During and After Cancer Treatment’, Acta Oncologica, 54(4), pp.581-586.
Morrison, V.A., McCall, L., Muss, H.B., Jatoi, A., Cohen, H.J., Cirrincione, C.T., Ligibel, J.A., Lafky, J.M., and Hurria, A. (2019) ‘The Impact of Actual Body Weight-Based Chemotherapy Dosing and Body Size on Adverse Events and Outcome in Older Patients with Breast Cancer: Results from Cancer and Leukemia Group B (CALGB) Trial 49907 (Alliance A151436)’, Journal of Geriatric Oncology, 9(3), pp.228-234.
National Comprehensive Cancer Network (2018) Cancer Related Fatigue. Available at: https://oncolife.com.ua/doc/nccn/fatigue.pdf. Accessed 13/12/2019.
National Health Service (2019) What is the Body Mass Index? Available at: https://www.nhs.uk/common-health-questions/lifestyle/what-is-the-body-ma.... Accessed 20/12/2019.
Persoon, S., ChinAPaw, M.J.M., Buffart, L.M., Liu, R.D.K., Wijermans, P., Koene, H.R., Minnema, M.C., Lugtenburg, P.J., Marijt, E.W.A., Brug, J., Nollet, F., and Kersten, M.J. (2017) ‘Randomized controlled trial on the effects of a supervised high intensity exercise program in patients with a hematologic malignancy treated with autologous stem cell transplantation: Results from the EXIST study’, PLoS ONE, 12(7), pp.1-14.
Ploutz-Snyder, L.L., Downs, M., Goetchius, E., Crowell, B., English, K.L., Ploutz-Snyder, R., Ryder, J.W., Dillon, E.L., Sheffield-Moore, M., and Scott, J.M. (2018) ‘Exercise Training Mitigates Multisystem Deconditioning during Bed Rest’, Medicine and Science in Sports and Exercise, 50(9), pp.1920-1928.
Sarfati, D., and Koczwara, B. (2016) ‘The Impact of Comorbidity on Cancer and Its Treatment’, A Cancer Journal for Clinicians, 66(4), pp.337-350.
Shachar, S.S., and Williams, G.R. (2017) ‘The Obesity Paradox in Cancer – Moving Beyond BMI’, Cancer Epidemiology, Biomarkers and Prevention, 26(1), pp.13-16.
Strati, P., Parikh, S.A., Chaffee, K.G., Kay, N.E., Call, T.G., Achenbach, S.J., Cerhan, J.R., Slager, S.L., and Shanafelt, T.D. (2017) ‘Relationship between Co-Morbidities at Diagnosis, Survival and Ultimate Cause of Death in Patients with Chronic Lymphocytic Leukaemia (CLL): A Prospective Cohort Study’, British Journal of Haematology, 178(3), pp.394–402.
Sung, C. and Herbst, J.L. (2017) ‘The ethics of caring for hospital-dependent patients’, BMC Medical Ethics, 18(1), pp 75-75.
Vallerand, J.R., Rhodes, R.E., Walker, G.J., and Courneya, K.S. (2018) ‘Feasibility and preliminary efficacy of an exercise telephone counselling intervention for hematologic cancer survivors: a phase II randomized controlled trial’, Journal of Cancer Survivorship, 12(3), pp.357-370.
World Health Organisation (2019) Physical Activity. Available at: https://www.who.int/dietphysicalactivity/pa/en/. Accessed 20/11/2019.